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1

Accelerating perfusion process optimization by scanning non-steady-state responses

Sumitra Angepat, Volker M. Gorenflo, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

2

Error propagation from prime variables into specific rates and metabolic fluxes for mammalian cells in perfusion culture

Chetan T. Goudar, Richard Biener, Konstantin B. Konstantinov, James M. Piret

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 519 KB

english, 2009

3

Estimating cell specific oxygen uptake and carbon dioxide production rates for mammalian cells in perfusion culture

Chetan T. Goudar, James M. Piret, Konstantinov B. Konstantinov

Journal:

Biotechnology Progress

Year:

2011

Language:

english

File:

PDF, 547 KB

english, 2011

4

Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy

Chetan Goudar, Richard Biener, C. Boisart, Rüdiger Heidemann, James Piret, Albert de Graaf, Konstantin Konstantinov

Journal:

Metabolic Engineering

Year:

2010

Language:

english

File:

PDF, 470 KB

english, 2010

5

Logistic Equations Effectively Model Mammalian Cell Batch and Fed-Batch Kinetics by Logically Constraining the Fit

Chetan T. Goudar, Klaus Joeris, Konstantin B. Konstantinov, James M. Piret

Journal:

Biotechnology Progress

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

6

Mammalian cell retention devices for stirred perfusion bioreactors

Steven M. Woodside, Bruce D. Bowen, James M. Piret

Journal:

Year:

1998

Language:

english

File:

PDF, 237 KB

english, 1998

7

Dependence on glucose limitation of the pCO2 influences on CHO cell growth, metabolism and IgG production

Shinya Takuma, Chikashi Hirashima, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 228 KB

english, 2007

8

Robust parameter estimation during logistic modeling of batch and fed-batch culture kinetics

Chetan T. Goudar, Konstantinov B. Konstantinov, James M. Piret

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

9

Basal medium composition and serum or serum replacement concentration influences on the maintenance of murine embryonic stem cells

Muhammad A. Chaudhry, Timothy Z. Vitalis, Bruce D. Bowen, James M. Piret

Journal:

Year:

2008

Language:

english

File:

PDF, 323 KB

english, 2008

10

Batch and Semicontinuous Aggregation and Sedimentation of Hybridoma Cells by Acoustic Resonance Fields

Phylis W. S. Pui, Felix Trampler, Stefan A. Sonderhoff, Martin Groeschl, Douglas G. Kilburn, James M. Piret

Journal:

Biotechnology Progress

Year:

1995

Language:

english

File:

PDF, 1.70 MB

english, 1995

11

Heat Transmission from Fine Wires to Water - Low Velocity Data and Correlation

Piret, Edgar L., James, Walter, Stacy, Maurice

Journal:

Industrial & Engineering Chemistry

Year:

1947

Language:

english

File:

PDF, 659 KB

english, 1947

12

Development of GMP-Compatible Protocols for Thymus-Derived Regulatory T Cell Expansion

MacDonald, Katherine, Hoeppli, Romy, Piret, James, Dijke, Esmé, West, Lori, Levings, Megan

Journal:

Transplantation Journal

Year:

2017

Language:

english

File:

PDF, 5.92 MB

english, 2017

13

Developing Fully Automated Quality Control Methods for Preprocessing Raman Spectra of Biomedical and Biological Samples

Schulze, H. Georg, Rangan, Shreyas, Piret, James M., Blades, Michael W., Turner, Robin F. B.

Journal:

Applied Spectroscopy

Year:

2018

Language:

english

File:

PDF, 2.60 MB

english, 2018

14

Differential stability of proteolytically active and inactive recombinant metalloproteinase in Chinese hamster ovary cells

Charlotte J. Morrison, W. Robert McMaster, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

15

Predictive control of hollow-fiber bioreactors for the production of monoclonal antibodies

Jason E. Dowd, Ingrid Weber, Beatriz Rodriguez, James M. Piret, K. Ezra Kwok

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 182 KB

english, 1999

16

Modification of a recombinant GPI-anchored metalloproteinase for secretion alters the protein glycosylation

Charlotte J. Morrison, Richard L. Easton, Howard R. Morris, W. Robert McMaster, James M. Piret, Anne Dell

Journal:

Biotechnology and Bioengineering

Year:

2000

Language:

english

File:

PDF, 607 KB

english, 2000

17

Effects of free convection on three-dimensional protein transport in hollow-fiber bioreactors

Marek Łabȩcki, James M. Piret, Bruce D. Bowen

Journal:

Year:

2004

Language:

english

File:

PDF, 782 KB

english, 2004

18

Protein transport in ultrafiltration hollow-fiber bioreactors

Anant Y. Patkar, Jürgen Koska, David G. Taylor, Bruce D. Bowen, James M. Piret

Journal:

Year:

1995

Language:

english

File:

PDF, 1.08 MB

english, 1995

19

Measurement of ultrasonic forces for particle–liquid separations

Steven M. Woodside, Bruce D. Bowen, James M. Piret

Journal:

Year:

1997

Language:

english

File:

PDF, 1.02 MB

english, 1997

20

Acoustic force distribution in resonators for ultrasonic particle separation

Steven M. Woodside, James M. Piret, Martin Gröschl, Ewald Benes, Bruce D. Bowen

Journal:

Year:

1998

Language:

english

File:

PDF, 918 KB

english, 1998

21

Glucose-based optimization of CHO-cell perfusion cultures

Jason E. Dowd, K. Ezra Kwok, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

22

Controlled shear affinity filtration (CSAF): A new technology for integration of cell separation and protein isolation from mammalian cell cultures

Jens H. Vogel, Birger Anspach, Karl-Heinz Kroner, James M. Piret, Charles A. Haynes

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

23

Scale-up and optimization of an acoustic filter for 200 L/day perfusion of a CHO cell culture

Volker M. Gorenflo, Laura Smith, Bob Dedinsky, Bo Persson, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

24

Common and distinct features of cytokine effects on hematopoietic stem and progenitor cells revealed by dose–response surface analysis

Julie Audet, Cindy L. Miller, Connie J. Eaves, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 226 KB

english, 2002

25

Empirical models of the proliferative response of cytokine-dependent hematopoietic cell lines

Muhammad A.S. Chaudhry, Bruce D. Bowen, Connie J. Eaves, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2004

Language:

english

File:

PDF, 457 KB

english, 2004

26

Characterization and optimization of acoustic filter performance by experimental design methodology

Volker M. Gorenflo, Joachim B. Ritter, Dana S. Aeschliman, Hans Drouin, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

27

Optical analysis of perfusion bioreactor cell concentration in an acoustic separator

Volker M. Gorenflo, Vincent S. Chow, Christopher Chou, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

28

Decreased pCO2 accumulation by eliminating bicarbonate addition to high cell-density cultures

Chetan T. Goudar, Ricaredo Matanguihan, Edward Long, Christopher Cruz, Chun Zhang, James M. Piret, Konstantin B. Konstantinov

Journal:

Biotechnology and Bioengineering

Year:

2007

Language:

english

File:

PDF, 284 KB

english, 2007

29

Mathematical model of the rate-limiting steps for retrovirus-mediated gene transfer into mammalian cells

Venkata S. Tayi, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

30

Effect of cell lysates on retroviral transduction efficiency of cells in suspension culture

Pascal R. Beauchesne, Katherine J. Bruce, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 520 KB

english, 2010

31

Pancreatic cell immobilization in alginate beads produced by emulsion and internal gelation

Corinne A. Hoesli, Kamini Raghuram, Roger L.J. Kiang, Dušana Mocinecová, Xiaoke Hu, James D. Johnson, Igor Lacík, Timothy J. Kieffer, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

32

Mammalian cell and protein distributions in ultrafiltration hollow fiber bioreactors

James M. Piret, Charles L. Cooney

Journal:

Biotechnology and Bioengineering

Year:

1990

Language:

english

File:

PDF, 1.03 MB

english, 1990

33

Model of oxygen transport limitations in hollow fiber bioreactors

James M. Piret, Charles L. Cooney

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

34

Analysis of mammalian viable cell biomass based on cellular ATP

Stefan A. Sonderhoff, Douglas G. Kilburn, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

1992

Language:

english

File:

PDF, 552 KB

english, 1992

35

Protein adsorption in polysulfone hollow fiber bioreactors used for serum-free mammalian cell culture

Anant Y. Patkar, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology and Bioengineering

Year:

1993

Language:

english

File:

PDF, 728 KB

english, 1993

36

Simpler noninstrumented batch and semicontinuous cultures provide mammalian cell kinetic data comparable to continuous and perfusion cultures

Olivier Henry, Ezra Kwok, James M. Piret

Journal:

Biotechnology Progress

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

37

A novel alginate hollow fiber bioreactor process for cellular therapy applications

Corinne A. Hoesli, Minh Luu, James M. Piret

Journal:

Biotechnology Progress

Year:

2009

Language:

english

File:

PDF, 457 KB

english, 2009

38

Raman microspectroscopic evidence that dry-fixing preserves the temporal pattern of non-specific differentiation in live human embryonic stem cells

Stanislav O. Konorov, H. Georg Schulze, Nicolas J. Caron, James M. Piret, Michael W. Blades, Robin F. B. Turner

Journal:

Journal of Raman Spectroscopy

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

39

Evidence of marked glycogen variations in the characteristic Raman signatures of human embryonic stem cells

Stanislav O. Konorov, H. Georg Schulze, James M. Piret, Robin F. B. Turner, Michael W. Blades

Journal:

Journal of Raman Spectroscopy

Year:

2011

Language:

english

File:

PDF, 387 KB

english, 2011

40

Two-dimensional analysis of protein transport in the extracapillary space of hollow-fibre bioreactors

Marek Łabȩcki, Bruce D. Bowen, James M. Piret

Journal:

Chemical Engineering Science

Year:

1996

Language:

english

File:

PDF, 1.39 MB

english, 1996

41

Mammalian cell culture processes

Wei-Shou Hu, James M. Piret

Journal:

Current Opinion in Biotechnology

Year:

1992

Language:

english

File:

PDF, 536 KB

english, 1992

42

Culture pH and osmolality influence proliferation and embryoid body yields of murine embryonic stem cells

Muhammad A. Chaudhry, Bruce D. Bowen, James M. Piret

Journal:

Biochemical Engineering Journal

Year:

2009

Language:

english

File:

PDF, 980 KB

english, 2009

43

Protein transport in packed-bed ultrafiltration hollow-fibre bioreactors

Jürgen Koska, Bruce D. Bowen, James M. Piret

Journal:

Chemical Engineering Science

Year:

1997

Language:

english

File:

PDF, 1.18 MB

english, 1997

44

Advances in hematopoietic stem cell culture

Julie Audet, Peter W Zandstra, Connie J Eaves, James M Piret

Journal:

Current Opinion in Biotechnology

Year:

1998

Language:

english

File:

PDF, 551 KB

english, 1998

45

Predictive modeling and loose-loop control for perfusion bioreactors

Jason E. Dowd, K.Ezra Kwok, James M. Piret

Journal:

Biochemical Engineering Journal

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

46

Production of a self-activating CBM-factor X fusion protein in a stable transformed Sf9 insect cell line using high cell density perfusion culture

Volker M. Gorenflo, Tom A. Pfeifer, Gary Lesnicki, Emily M. Kwan, Thomas A. Grigliatti, Douglas G. Kilburn, James M. Piret

Journal:

Year:

2004

Language:

english

File:

PDF, 134 KB

english, 2004

47

Two-dimensional analysis of fluid flow in hollow-fibre modules

Marek Łabȩcki, James M. Piret, Bruce D. Bowen

Journal:

Chemical Engineering Science

Year:

1995

Language:

english

File:

PDF, 1.30 MB

english, 1995

48

Increased t-PA Yields Using Ultrafiltration of an Inhibitory Product from CHO Fed-Batch Culture

Jason E. Dowd, K. Ezra Kwok, James M. Piret

Journal:

Biotechnology Progress

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

49

Optimization of an Acoustic Cell Filter with a Novel Air-Backflush System

Volker M. Gorenflo, Sumitra Angepat, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology Progress

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

50

Cell Separator Operation within Temperature Ranges To Minimize Effects on Chinese Hamster Ovary Cell Perfusion Culture

Hans Drouin, Joachim B. Ritter, Volker M. Gorenflo, Bruce D. Bowen, James M. Piret

Journal:

Biotechnology Progress

Year:

2007

Language:

english

File:

PDF, 367 KB

english, 2007